Published in Hepatitis Weekly, December 29th, 2008
"The mechanisms of antibody-mediated neutralization by host neutralizing responses in HCV infection are only poorly understood. Retroviral HCV pseudotypes (HCVpp) and recombinant cell culture-derived HCV (HCVcc) have been successfully used to study viral entry and antibody-mediated neutralization. in this study, we used these model systems to investigate the mechanism of antibody-mediated neutralization...
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