Hepatitis C Virus
Research data from Pohang University of Science and Technology update understanding of hepatitis C virus
Published in Hepatitis Weekly, January 26th, 2009
"Here, we report that a cellular protein, hnRNP D, interacts with the 5' border of HCV IRES (stem-loop II) and promotes translation of HCV mRNA. Overexpression of hnRNP D in mammalian cells enhances HCV IRES-dependent translation, whereas knockdown of hnRNP D with small interfering RNAs (siRNAs) inhibits translation. In addition, sequestration...
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Source: Hepatitis Weekly (2009-01-26)
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