Alzheimer Disease

Scientists at University of Antwerp publish new data on Alzheimer disease

Published in Hepatitis Weekly, February 2nd, 2009

"Alzheimer's disease (AD) is the leading cause of dementia. It is characterized by the presence of senile plaques and neurofibrillary tangles in the brain, and impairment of the central cholinergic system, which contribute to memory toss and cognitive dysfunction," scientists in Antwerp, Belgium report.

"Cholinesterase inhibitors prevent the hydrolysis of acetylcholine and are currently approved for the symptomatic treatment of Alzheimer's disease. Donepezil, a piperidine-based, reversible and specific inhibitor of acetylcholinesterase, has been demonstrated to be clinically effective in the treatment of patients with mild to moderate AD. To date, clinical trials have...

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Source: Hepatitis Weekly (2009-02-02)

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