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Hepatitis A Virus

New findings from N. Shimasaki and co-authors describe advances in hepatitis A virus

Published in Hepatitis Weekly, February 2nd, 2009

According to recent research published in the journal Vox Sanguinis, "Hepatitis A virus (HAV) transmission via contaminated blood products has been reported. Cell-adapted HAV strains are generally used to confirm virus inactivation in manufacturing blood products, but the strains may differ in their sensitivity to inactivation treatment."

"To select an appropriate cell-adapted HAV strain for virus validation, we compared the inactivation efficiency among four strains under two different physical inactivation treatments: heat and high hydrostatic pressure. The cell-adapted HAV strains used here were KRM238, KRM003 (subgenotype IIIB), KRM031 (IA), and TKM005 (IB)....

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