Hepatitis C Virus Cell Biology
Data from Center for the Study of Hepatitis C provide new insights into hepatitis C virus cell biology
Published in Hepatitis Weekly, February 16th, 2009
New research, 'Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection,' is the subject of a report. "Perisinusoidal hepatic stellate cells (HSC) are the principal fibrogenic cells in the liver. In animal models, HSC apoptosis is the predominant clearance mechanism of activated HSC, although data evaluating whether the same processes occur in humans are limited," investigators in the United States report.
"We conducted a cross-sectional study to evaluate the association between HSC apoptosis and fibrosis stage in subjects with chronic hepatitis C virus (HCV) infection (n=44) and HCV-negative controls with normal...
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Source: Hepatitis Weekly (2009-02-16)
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