Cold Spring Harbor Laboratory
Camouflaging of viral DNA could be crucial step in progression of cancers
Published in Hepatitis Weekly, February 23rd, 2009
An estimated 15% of cancer cases can be linked to a viral infection, however the biological changes that cause some asymptomatic carriers of a virus to develop full-blown tumors are not well understood. In a study published online in Genome Research (www.genome.org), scientists have mapped a chemical modification of DNA in three oncogenic viruses (Epstein-Barr, human papilloma virus, and hepatitis B virus) and found that the viral genome undergoes critical changes during the progression of disease, with implications for the development of new methods of prevention, diagnosis, and treatment.
Worldwide, most people are already infected with the Epstein-Barr virus, and...
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Source: Hepatitis Weekly (2009-02-23)
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