Hepatitis C Virus
New hepatitis C virus study findings have been reported by Z.F. Tian and colleagues
Published in Hepatitis Weekly, March 9th, 2009
In this recent study, researchers in Wuhan, People's Republic of China conducted a study "To further analyze the interaction of tupaia CD81 with hepatitis C virus (HCV) envelope protein E2. A tupaia CD81 large extracellular loop (CD81 LEL), which binds to HCV E2 protein, was cloned and expressed as a GST-fusion protein, and interaction of HCV E2 protein with a tupaia CD81 LEL was evaluated by enzyme-linked immunosorbent assay (EIA)."
"Although tupaia and human CD81 LEL differed in 6 amino acid changes, tupaia CD81 LEL was strongly recognized by anti-CD81 antibodies against human CD81 LEL conformation-dependent epitopes. Investigating LEL CD81-E2 interactions by EIA, we...
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Source: Hepatitis Weekly (2009-03-09)
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