Immunoassay

Studies from Xiamen University yield new information about immunoassay

Published in Hepatitis Weekly, March 9th, 2009

"Despite their ease of use, lateral flow immunoassays (LFIAs) often suffer from poor quantitative discrimination and low analytical sensitivity. We explored the use of a novel class of europium chelate-loaded silica nanoparticles as labels to overcome these limitations," scientists in Xiamen, People's Republic of China report.

"Antibodies were covalently conjugated onto europium chelate-loaded silica nanoparticles with dextran as a linker. The resulting conjugates were used as labels in LFIA for detection of hepatitis B surface antigen (HBsAg). We performed quantification with a digital camera and Adobe Photoshop software. We also used 286 clinical samples to compare...

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Source: Hepatitis Weekly (2009-03-09)

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