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Hepatitis B Virus Therapy

Findings from University of Paris broaden understanding of hepatitis B virus therapy

Published in Hepatitis Weekly, March 9th, 2009

Current study results from the report, 'Impact of adefovir dipivoxil on liver fibrosis and activity assessed with biochemical markers (FibroTest-ActiTest) in patients infected by hepatitis B virus,' have been published. "The aim was to assess the utility of FibroTest-ActiTest (FT-AT) as noninvasive markers of histological changes in patients with chronic hepatitis. Patients with chronic hepatitis B (HBeAg+ and HBeAg-) randomized in two trials of adefovir (ADV) vs placebo, with available paired liver biopsies and FT-AT at baseline and after 48 weeks of treatment were included," researchers in Paris, France report.

The researchers concluded: "The aim was to assess the...

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