Hepatocellular Cancer

Research from T. Yamamoto and co-researchers in the area of hepatocellular cancer published

Published in Hepatitis Weekly, March 30th, 2009

According to a study from Nishinomiya, Japan, "Vitamin K-2 has been reported to suppress the growth of human hepatocellular carcinoma (HCC) in vitro and hepatocarcinogenesis in hepatitis C virus (HCV)-related cirrhosis in vivo. Hepatoma-derived growth factor (HDGF) is a unique nuclear targeting growth factor that is highly expressed in HCC cells and is a possible prognostic factor for patients with HCC."

"We investigated the regulation of HDGF expression by vitamin K-2. Three HCC-derived cell lines, HepG2, HuH-7, and SK-Hep-1, were used. Cell number was determined with the MTT assay. The expression levels of HDGF mRNA and protein were measured by the real-time reverse...

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Source: Hepatitis Weekly (2009-03-30)

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