DNA Research

Research data from C.L. Netherton and colleagues update understanding of DNA research

Published in Hepatitis Weekly, April 13th, 2009

"Increasing evidence points to the importance of the interferon (IFN) response in determining the host range and virulence of African swine fever virus (ASFV). Infection with attenuated strains of ASFV leads to the upregulation of genes controlled by IFN pathways, including myxovirus resistance (Mx) genes that are potent effectors of the antiviral state," scientists in Pirbright, the United Kingdom report.

"Mx gene products are known to inhibit the replication of many negative-sense single-stranded RNA viruses, as well as double-stranded RNA viruses, positive-sense single-stranded RNA viruses, and the reverse-transcribing DNA virus hepatitis B virus. Here, we provide...

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Source: Hepatitis Weekly (2009-04-13)

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