Cancer Gene Therapy
Researchers from Pusan National University publish findings in cancer gene therapy
Published in Hepatitis Weekly, April 27th, 2009
Scientists discuss in 'Expression of HBX, an oncoprotein of hepatitis B virus, blocks reoviral oncolysis of hepatocellular carcinoma cells' new findings in cancer gene therapy. According to recent research from Korea, "Although reovirus has been used in tests as a potential cancer therapeutic agent against a variety of cancer cells, its application to hepatocellular carcinoma cells, in which the hepatitis B virus (HBV) X (HBX) protein of HBV plays a primary role, has not yet been explored. Here, we describe experiments in which we use reovirus to treat Chang liver carcinoma cells expressing either a vector only (Chang-vec) or a vector encoding HBX protein (Chang-HBX)."
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Source: Hepatitis Weekly (2009-04-27)
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