Published in Hepatitis Weekly, May 11th, 2009
"We sought to investigate how Tregs are regulated in the livers of patients chronically infected with HCV, where they control the balance between an adequate protective immune response and suppression of immunopathology. We found that, despite accumulating and proliferating at sites of infection in the livers of patients chronically infected with HCV, Tregs were relatively less expanded than CD4(+)CD25(+)Foxp3(-) effector T cells. The relative lower expansion...
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