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Hepatocellular Cancer

Research on hepatocellular cancer discussed by scientists at University of Hong Kong

Published in Hepatitis Weekly, May 11th, 2009

According to a study from Hong Kong, People's Republic of China, "Hepatocellular carcinoma (HCC) is an aggressive liver cancer but clinically validated biomarkers that can predict natural history of malignant progression are lacking. The present study explored the proteome-wide patterns of HCC to identify biomarker signature that could distinguish cancerous and nonmalignant liver tissues."

"A retrospective cohort of 80 HBV-associated HCC was included and both the tumor and adjacent nontumor tissues were subjected to proteome-wide expression profiling by 2-DE method. The subjects were randomly divided into the training (n = 55) and validation (n = 25) subsets, and the...

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