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Hepatocellular Cancer

Researchers from Kanazawa University, Medical Department report recent findings in hepatocellular cancer

Published in Hepatitis Weekly, May 25th, 2009

"MicroRNA (miRNA) plays an important role in the pathology of various diseases, including infection and cancer. Using real-time polymerase chain reaction, we measured the expression of 188 miRNAs in liver tissues obtained from 12 patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) and 14 patients with hepatitis C virus (HCV)-related HCC, including background liver tissues and normal liver tissues obtained from nine patients," investigators in Kanazawa, Japan report.

"Global gene expression in the same tissues was analyzed via complementary DNA microarray to examine whether the differentially expressed miRNAs could regulate their target genes....

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