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Immunization

Research on immunization discussed by R.P.M. Koene and co-researchers

Published in Hepatitis Weekly, May 25th, 2009

According to recent research published in the journal Epidemiology and Infection, "In the Dutch national vaccination campaign for behavioural risk groups, anti-HBcore is used as the primary HBV screening test. Samples with positive results undergo testing for active infection (HBsAg) but are otherwise accepted as indicating past infection, thereby assuming immunity."

"This study evaluated evidence for immunity in the target population screened on the basis of this algorithm, by re-analysing 1000 anti-HBcore-positive blood samples equally divided among risk groups: 14.% of confirmed anti-HBcore lacked anti-HBs ('isolated' anti-HBcore). Independent risk factors for...

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