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HIV/AIDS

Research from New York University reveals new findings on HIV/AIDS

Published in Hepatitis Weekly, June 8th, 2009

"Patients with HIV-1 immune-related thrombocytopenia (HIV-1-ITP) have a unique Ab against platelet GPIIIa49-66 capable of inducing oxidative platelet fragmentation in the absence of complement. HIV-1 seropositive drug abusers are more prone to develop immune thrombocytopenia than non-drug abusers and have a higher coinfection with hepatitis C virus (HCV) than non-drug abusers (90% vs 30%)," scientists in the United States report.

"Molecular mimicry was sought by screening a phage peptide library with anti GPIIIa49-66 antibody as bait for peptides sharing homology sequences with HCV. Several phage peptide clones had 70% homology with HCV protein. Sera from dually...

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