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Hepatitis Weekly

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Hepatitis B Virus



Data on hepatitis B virus discussed by researchers at National Taiwan University, Medical Department



June 15th, 2009

According to recent research from Taipei, Taiwan, "With the exception of alanine aminotransferase (ALT) level, baseline factors predictive of therapeutic response to lamivudine in patients with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) remain unknown. We thus studied the influence of pre-therapy viral factors on end-of-treatment responses to lamivudine."

"A total of 116 treatment-naive HBeAg-positive CHB patients who had pre-therapy ALT level >5x the upper limit of normal (ULN) and received lamivudine for 12-18 months were enrolled. HBeAg seroclearance and combined Hi seroclearance, ALT normalization and undetectable hepatitis B virus DNA at...


Source: Hepatitis Weekly (2009-06-15)

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