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Hepatitis B Virus
New findings reported from University of Michigan describe advances in hepatitis B virus
June 15th, 2009
"The aim of this review is to summarize the safety profile of the five approved oral nucleoside analogs used to treat chronic hepatitis B virus (HBV) infection, focusing on both the class adverse effects and those that have been reported with individual agents, as well as their safety in pregnancy. All nucleoside analogs have a ''Black Box'' warning because of their potential for inhibition of human DNA polymerase gamma involved in mitochondrial DNA replication," scientists in the United States report. "A reduction in intracellular mitochondrial. DNA levels can lead to varying clinical manifestations of mitochondrial toxicity (i.e., neuropathy, myopathy, lactic...
Source: Hepatitis Weekly (2009-06-15)
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