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Acute Hepatitis
Reports outline acute hepatitis research from Medical University of Vienna
June 15th, 2009
"While the adaptive immune response is crucial for spontaneous resolution of acute hepatitis C virus (HCV) infection, it also constitutes the driving force for viral escape. For acutely HCV-infected dialysis patients, little is known about the host response and its impact on viral evolution," scientists writing in the Journal of Hepatology report. "Four haemodialysis patients accidentally infected with the same HCV strain were prospectively investigated with respect to the clinical course, CD4+ and CD8+ T-cell responses, neutralizing antibodies, viral kinetics and sequence variability. In one patient, a robust CD4+ T-cell response was associated with transient...
Source: Hepatitis Weekly (2009-06-15)
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