Hepatitis C Virus
New findings from Kurume University in the area of hepatitis C virus described
Published in Hepatitis Weekly, June 15th, 2009
According to recent research from Kurume, Japan, "To investigate the association between hepatitis C virus (HCV) and B cell proliferation, we searched for the clonal B cells by flow cytometric analysis of the surface immunoglobulin kappa (kappa):lambda (lambda) light chain ratios of the circulating B (CD19+) cells in 240 HCV-positive patients and 150 negative controls with liver diseases. Clonal B cells with light chain restriction (kappa:lambda ratio > 3:1 or < 1:2) were analyzed for CD5 expression and the presence of monoclonal immunoglobulin heavy-chain (IGH) gene rearrangements and the t(14;18) chromosomal translocation."
"Clonal B cells were detected in 7...
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Source: Hepatitis Weekly (2009-06-15)
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