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Hepatitis Weekly

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Carcinoma



New findings from University of Zurich in the area of carcinoma described



June 15th, 2009

According to recent research from Zurich, Switzerland, "Hepatocellular carcinomas (HCCs) and bile duct carcinomas (BDCs) have a poor prognosis. Therefore, surveillance strategies including sensitive and specific serum markers for early detection are needed."

"Recently, Golgi Phosphoprotein 2 (GOLPH2) has been proposed as a serum marker for HCC but GOLPH2 expression data in liver tissues was not available. Using tissue microarrays and immunohistochemistry, we semiquantitatively analyzed GOLPH2 protein expression in patients with HCC (n = 170), benign liver tumors (n = 22), BDC (n = 114) and normal liver tissue (n = 105). A newly designed sandwich enzyme-linked...


Source: Hepatitis Weekly (2009-06-15)

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