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Hepatitis Weekly

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Cirrhosis



Study data from University of London, Imperial College update knowledge of cirrhosis



June 15th, 2009

"Observations that hepatic inflammation and cirrhosis are associated with the presence of thrombi within the hepatic microvasculature and fibrin-fibrinogen deposition have led to epidemiologic studies showing that carriage of the factor V Leiden mutation, protein C deficiency, and increased expression of factor VIII are associated with rapid progression to cirrhosis in a chronic hepatitis C virus. Additional data suggest that this process may extend more broadly to progression in many forms of chronic liver disease," scientists writing in the journal Clinics in Liver Disease report.

"This article discusses the evidence for a role for coagulation cascade activity...


Source: Hepatitis Weekly (2009-06-15)

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