Hepatitis Weekly
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Hepatitis B Virus
Studies from G.L.H. Wong and co-authors have provided new information about hepatitis B virus
July 13th, 2009
According to recent research published in the Journal of Gastroenterology and Hepatology, "The proposed cut-off values for the degree of fibrosis as assessed by liver stiffness measurement (LSM) might not be applicable in severe acute exacerbation of chronic hepatitis B (CHB). We aimed to assess the effect of necroinflammatory activity on LSM in this condition." "We prospectively recruited consecutive patients with severe acute exacerbation of CHB (alanine aminotransferase or ALT > 10x upper limit of normal). The relationship of ALT levels and LSM were serially assessed and liver biopsy was carried out after ALT normalization. Eleven patients (10 male, median...
Source: Hepatitis Weekly (2009-07-13)
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