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Hepatitis C Virus
New findings from Kobe University in the area of hepatitis C virus published
July 13th, 2009
According to a study from Kobe, Japan, "Persistent infection with hepatitis C virus (HCV) causes extrahepatic diseases, including diabetes. We investigated the possible effect(s) of HCV replication on cellular glucose uptake and expression of the facilitative glucose transporter (GLUT) 2 and 1. We used Huh-7.5 cells harboring either an HCV subgenomic RNA replicon (SGR) or an HCV full-genomic RNA replicon (FGR), HCV-infected cells, and the respective cells treated with interferon (1FN)." "We also used liver tissue samples obtained from patients with or without HCV infection. Glucose uptake and surface expression of GLUT2 and GLUT1 were suppressed in SGR, FGR and...
Source: Hepatitis Weekly (2009-07-13)
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