Hepatitis C Virus
Reports on hepatitis C virus findings from I. Benedicto and co-researchers provide new insights
Published in Hepatitis Weekly, September 21st, 2009
"Of these molecules, claudin-1, a tight junction (TJ) component, is considered a coreceptor required for HCV entry. Recently, we have demonstrated that HCV envelope glycoproteins (HCVgp) promote structural and functional TJ alterations. Additionally, we have shown that the intracellular interaction between viral E2 glycoprotein and occludin, another TJ-associated protein, could be the cause of the mislocalization of TJ proteins....
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Source: Hepatitis Weekly (2009-09-21)
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