Hepatitis C Virus
Data on hepatitis C virus detailed by M. Sillanpaa and co-authors
Published in Hepatitis Weekly, September 28th, 2009
According to a study from Helsinki, Finland, "The viral genome of hepatitis C virus constitutes a 9.6-kb single-stranded positive-sense RNA which encodes altogether 11 viral proteins. In order to study the humoral immune responses against different HCV proteins in patients suffering from chronic HCV infection, we produced three structural (core, E1 and E2) and six nonstructural proteins (NS2, NS3, NS4A, NS4B, NS5A and NS5B) in Sf9 insect cells by using the baculovirus expression system."
"The recombinant HCV core, E1, E2, NS2, NS3, NS4A, NS4B, NS5A and NS5B proteins were purified and used in Western blot analysis to determine antibody responses against individual HCV...
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Source: Hepatitis Weekly (2009-09-28)
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