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Hepatitis Therapy

Data from Mie University, Institute of Medical Science provide new insights into hepatitis therapy

Published in Hepatitis Weekly, October 5th, 2009

New research, 'Patients achieving clearance of HCV with interferon therapy recover from decreased retinol-binding protein 4 levels,' is the subject of a report. "Retinol-binding protein 4 (RBP4) is a recently identified adipokine that is elevated in the blood in several insulin-resistant states. We investigated the association between plasma RBP4 and histological and biochemical characteristics of chronic hepatitis C (CHC), as well as changes in RBP4 levels following interferon therapy," investigators in Tsu, Japan report.

"Eighty-one patients with CHC infected with genotype 1 received treatment with peginterferon plus ribavirin. Histological data were available for 41...

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