Hepatitis C Virus

Investigators at University of Heidelberg publish new data on hepatitis C virus

Published in Hepatitis Weekly, October 19th, 2009

"Recently, two functional IL18 promoter variants, -607C > A (rs1946518) and -137G > C (rs187238), were associated with viral clearance in patients with hepatitis C. The present study focused on their relevance for treatment response. Seven hundred fifty-seven chronically infected European patients and 791 controls were enrolled in the study," researchers in Mannheim, Germany report.

"IL18 genotyping was performed by allele-specific PCR. Liver histology was available in 67.9%. Genotype and allele frequencies were equally distributed in patients and controls. No significant association with various disease characteristics was observed. However, when comparing...

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Source: Hepatitis Weekly (2009-10-19)

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