RNA Research
New findings from Nankai University describe advances in RNA research
Published in Hepatitis Weekly, October 19th, 2009
In this recent report, researchers in Tianjin, People's Republic of China conducted a study "To explore the mechanism of hepatocarcinogenesis associated with the hepatitis B virus X protein (HBx), we investigated the role of HBx in transformation using human liver L-O2 cells stably transfected with HBx as a model. Plasmids encoding HBx were stably transfected into immortalized human liver L-O2 cells and rodent fibroblast NIH/3T3 cells."
"The expression of alfa-fetoprotein (AFP), c-Myc, HBx, and survivin in the engineered cells was examined by Western blotting. The malignant phenotype of the cells was demonstrated by anchorage-independent colony formation and tumor...
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Source: Hepatitis Weekly (2009-10-19)
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