Hepatocellular Cancer Genetics
Recent studies from Bambino Gesu Children's Hospital, Department of Pathology add new data to hepatocellular cancer genetics
Published in Hepatitis Weekly, October 26th, 2009
A report, 'Z and Mmalton-1-antitrypsin deficiency-associated hepatocellular carcinoma: a genetic study,' is newly published data in Liver International. According to recent research from Rome, Italy, "The histological hallmark of alpha-1-antitrypsin deficiency (AATD) is the presence of periodic acid-Schiff diastase (PASD)-resistant positive globules in hepatocytes, with a heterogeneous distribution. It is noteworthy that hepatocellular carcinoma (HCC) arises specifically from the AAT-negative areas but the reason for this remains unclear."
"To determine whether the different distribution of AAT globules within neoplastic and non-neoplastic hepatocytes is the...
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Source: Hepatitis Weekly (2009-10-26)
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