Hepatitis C Virus

Recent studies by H. Suzuki and co-authors add new data to hepatitis C virus findings

Published in Hepatitis Weekly, December 14th, 2009

According to recent research from Chiba, Japan, "Hepatitis C virus (HCV) is one of the main causes of liver-related morbidity and mortality. Although combined interferon-alpha-ribavirin therapy is effective for about 50% of the patients with HCV, better therapies are needed and preventative vaccines have yet to be developed."

"Short-hairpin RNAs (shRNAs) inhibit gene expression by RNA interference. The application of transient shRNA expression is limited, however, due to the inability of the shRNA to replicate in mammalian cells and its inefficient transduction. The duration of transgene (shRNA) expression in mammalian cells can be significantly extended using...

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Source: Hepatitis Weekly (2009-12-14)

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