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Hepatitis C Virus

Reports by E. Gruppioni and co-researchers describe recent advances in hepatitis C virus

Published in Hepatitis Weekly, January 18th, 2010

According to recent research published in the journal Diagnostic Molecular Pathology, "The assessment of hepatitis C virus (HCV) RNA in liver tissues is clinically relevant in cases where histology, liver function tests, and HCV serology are not sufficient for a definitive diagnosis of HCV-related hepatitis. We analyzed 215 formalin-fixed, paraffin-ern bedded liver needle biopsies from patients infected with HCV genotypes 1b and 2. HCV RNA extracted from paraffin sections were quantified by means of a TaqMan real-time reverse transcription-polymerase chain reaction method."

"The quantification of HCV RNA in liver tissue was correlated with the amount of HCV...

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