Dengue Fever
Studies from R.A. Agisjuarez and colleagues provide new data on dengue fever
Published in Hepatitis Weekly, January 25th, 2010
"The 3' untranslated region (3'UTR) of the dengue virus (DENV) genome contain several sequences required for translation, replication and cyclization processes. This region also binds cellular proteins such as La, polypyrimidine tract-binding protein (PTB), Y box-binding protein 1, poly(A)-binding protein and the translation initiation factor eEF-1 alpha, PTB is a cellular protein that interacts with the regulatory sequences of positive-strand RNA viruses such as several picornaviruses and hepatitis C virus," scientists writing in the Journal of General Virology report.
"In the present report, it was demonstrated that PTB translocates from the nucleus to the...
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Source: Hepatitis Weekly (2010-01-25)
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