Hepatitis C Virus
Reports summarize hepatitis C virus study results from University Hospital
Published in Hepatitis Weekly, February 8th, 2010
According to recent research published in the Journal of Hepatology, "While hepatic stellate cells (HSC) are known to be key mediators of liver fibrosis, only little is known about their functional role in the innate immune system of the liver. To address this question, murine HSC were isolated from livers of C57BL/6J mice and human HSC were isolated from liver samples obtained from resections and liver explants."
"HSC were stimulated with Toll-like receptor (TLR) 1-9 ligands for 20 h. Supernatants were harvested and used in virus protection assays (encephalomyocarditis virus, EMCV) as well as in human and murine hepatitis C virus (HCV) replicon systems....
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Source: Hepatitis Weekly (2010-02-08)
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