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Hepatitis B Virus Genetics

Studies from Second Military Medical University, Department of Laboratory Medicine reveal new findings on hepatitis B virus genetics

Published in Hepatitis Weekly, March 8th, 2010

Research findings, 'An intronic polymorphism in the corticotropin-releasing hormone receptor 2 gene increases susceptibility to HBV-related hepatocellular carcinoma in Chinese population,' are discussed in a new report. According to recent research from Shanghai, People's Republic of China, "Corticotropin-releasing hormone receptor 2 (CRHR2) plays a role in both the central nervous system (CNS) and the peripheral nervous system. CRHR2 together with its ligands, urocortins (Ucns) and corticotropin-releasing hormone (CRH), functions as a mediator of inflammatory response and inhibitor of angiogenesis."

"Recently, it has been reported to be expressed in many human cancers....

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