Hepatitis C Virus Genetics
Investigators at Toranomon Hospital have published new data on hepatitis C virus genetics
Published in Hepatitis Weekly, March 15th, 2010
Investigators publish new data in the report 'Influence of amino-acid polymorphism in the core protein on progression of liver disease in patients infected with hepatitis C virus genotype 1b.' "The substitution of amino acid (aa) 70 of arginine for glutamine and/or that of aa91 of leucine for methionine in the core protein in patients infected with hepatitis C virus (HCV) genotype 1b is associated with a poor response to pegylated interferon and ribavirin. Factors influencing these substitutions were sought in 1,097 patients infected with HCV-1b who had not received antiviral treatment," investigators in Tokyo, Japan report.
"HCV variants with Arg70 and Leu91...
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Source: Hepatitis Weekly (2010-03-15)
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