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Hepatitis E Virus

New hepatitis E virus research has been reported by N. Rose et al

Published in Hepatitis Weekly, April 19th, 2010

"In the absence of commercial kits for serological studies specifically for hepatitis E virus (HEV) infection of swine, the capsid protein of a swine genotype 3 HEV was expressed using a recombinant baculovirus. This antigen was used in an enzyme-linked immunosorbent assay (ELISA) for detection of anti-HEV antibodies," scientists in Maisons-Alfort, France report.

"Estimation of sensitivity and specificity was carried out in comparison with a commercial serological assay using sera from pigs infected experimentally with HEV genotype 3, negative sera from SPF pigs and swine sera collected at slaughterhouses. Since a ''gold standard'' is not available, a latent-class...

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