Hepatitis C Virus Genetics
Reports outline hepatitis C virus genetics research from S.M. Nakatani and colleagues
Published in Hepatitis Weekly, May 3rd, 2010
New investigation results, 'Development of hepatitis C virus genotyping by real-time PCR based on the NS5B region,' are detailed in a study published in PloS One. "Hepatitis C virus (HCV) genotyping is the most significant predictor of the response to antiviral therapy. The aim of this study was to develop and evaluate a novel real-time PCR method for HCV genotyping based on the NS5B region," investigators in Parana, Brazil report.
"Two triplex reaction sets were designed, one to detect genotypes 1a, 1b and 3a; and another to detect genotypes 2a, 2b, and 2c. This approach had an overall sensitivity of 97.0%, detecting 295 of the 304 tested samples. All samples...
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Source: Hepatitis Weekly (2010-05-03)
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