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Hepatitis Delta Virus

Studies from Southern Medical University, Department of Radiation Oncology describe new findings in hepatitis delta virus

Published in Hepatitis Weekly, May 10th, 2010

Data detailed in 'Efficient inhibition of hepatitis B virus replication by hepatitis delta virus ribozymes delivered by targeting retrovirus' have been presented. "Hepatitis delta virus (HDV) ribozyme is an attractive molecular tool that can specifically recognize and catalyze the self-cleavage of the viral RNA phosphodiester backbone. However, a major obstacle in the medical application of the HDV ribozyme is the lack of specificity in the delivery of the ribozyme to defined target cells," scientists writing in the Virology Journal report.

"The objective of this study was to determine whether retroviral vectors can deliver the HDV ribozyme into the target cells...

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