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Insulin Resistance

Recent findings from M. Khattab and co-authors highlight research in insulin resistance

Published in Hepatitis Weekly, May 31st, 2010

A new study, 'Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance,' is now available. According to recent research from Egypt, "Insulin resistance (IR) affects sustained virological response (SVR). The use of insulin-sensitizing agents has been proposed to improve therapy outcome."

"The safety and efficacy of pioglitazone on insulin sensitivity and SVR in treatment-naive patients with chronic hepatitis C (CHC) genotype 4 with IR receiving standard antiviral therapy were evaluated in a randomized-controlled study. Ninety-seven previously untreated patients with CHC...

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