Metalloendopeptidases
Research data from Chang Gung Memorial Hospital update understanding of metalloendopeptidases
Published in Hepatitis Weekly, June 7th, 2010
"Serum matrix metalloproteinase (MMP)-9/MMP-2 ratios are highly associated with alpha-fetoprotein levels in patients with chronic hepatitis B. In this study, we evaluate the clinical usefulness of this ratio as a biomarker in hepatitis B virus-related hepatocellular carcinoma (HCC). Serum samples from 181 chronic hepatitis B patients (52 healthy carriers, 47 chronic hepatitis patients, 50 cirrhosis patients, and 32 HCC patients) were collected," researchers in Taipei, Taiwan report.
"MMP-9/MMP-2 ratio was determined by zymography. The results were analyzed using the Receiver-Operating Characteristic (ROC) curve. Serum MMP-91MMP-2 ratios in HCC patients were...
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Source: Hepatitis Weekly (2010-06-07)
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