Hepatitis

Research from Texas Technical University in the area of hepatitis described

Published in Hepatitis Weekly, June 7th, 2010

According to recent research from the United States, "To test the hypothesis that particle size influences the magnitude of immune response produced by hepatitis B surface antigen (HBsAg) encapsulated in poly (lactic-co-glycolic acid) (PLGA) microspheres. Microspheres were prepared by a double-emulsion-solvent-evaporation method, and the particles were characterized for size, morphology, porosity and antigen content."

"Immunogenicity of encapsulated antigen and safety were studied in rats. Uptake of fluorescent-labeled particles by rat alveolar macrophages was studied by confocal microscopy. With increasing internal aqueous phase (IAP) volume of the microsphere, an...

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Source: Hepatitis Weekly (2010-06-07)

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