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Chronic Hepatitis B Virus

Studies from University Medical Center update current data on chronic hepatitis B virus

Published in Hepatitis Weekly, June 7th, 2010

Fresh data on chronic hepatitis B virus are presented in the report 'Antiviral effect of entecavir in chronic hepatitis B: influence of prior exposure to nucleos(t)ide analogues.' "Entecavir is a potent inhibitor of viral replication in nucleos(t)ide analogue (NA)-naive chronic hepatitis B patients, but data on the efficacy in NA-experienced subjects are limited. In a multi-center cohort study we investigated 161 chronic hepatitis B patients (34% NA-experienced) treated with entecavir monotherapy," scientists in Rotterdam, Netherlands report.

"During a median follow-up of 11 (3-23)months, 82 (79%) of 104 NA-naive patients achieved virologic response (VR), defined as HBV...

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