Hepatitis B Virus

Investigators at Nankai University have published new data on hepatitis B virus

Published in Hepatitis Weekly, June 7th, 2010

"Hepatitis B virus (HBV) infection is closely correlated with the development of hepatocellular carcinoma (HCC), in which hepatitis B virus X protein (HBx) plays crucial roles. HBx is believed to be a multifunctional oncoprotein," researchers in Tianjin, People's Republic of China report.

"It has been reported that the calpain small subunit 1 (Capn4) is upregulated in the HCC tissues and involved in the metastasis of HCC Therefore, we suppose that HBx may promote hepatoma cell migration through Capn4. In the present study, we investigated the effect of HBx on regulating Capn4 expression in human HCC cells. Our data showed that HBx could increase promoter activity of...

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Source: Hepatitis Weekly (2010-06-07)

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