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Hepatitis C Virus

Presidio Pharmaceuticals, Inc. Selects Second Clinical Candidate from Hepatitis C Virus NS5A Inhibitor Program

Published in Hepatitis Weekly, June 7th, 2010

Presidio Pharmaceuticals, Inc. announced that they have selected a second clinical candidate, PPI-1301, from their hepatitis C virus (HCV) NS5A program for advancement into clinical development. Presidio's first NS5A inhibitor, PPI-461, is currently undergoing evaluation in a Phase 1a clinical study.

Inhibitors of the HCV NS5A protein represent an exciting, highly potent class that is distinct from other classes of HCV antivirals that target the viral protease or replicase. With poor response and tolerance issues associated with the current standard of care treatment-pegylated-IFN and ribavirin-there is clear need for more potent and better tolerated inhibitors that can...

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