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Interferon Type I

Findings from H. Toyoda et al in interferon type i reported

Published in Hepatitis Weekly, September 6th, 2010

"As combination therapy with peginterferon (PEG-IFN) and ribavirin has a high morbidity, identifying individuals with hepatitis C virus (HCV) who will not respond to the treatment would be beneficial. The early responses of serum HCV RNA levels to standard interferon (IFN) and PEG-IFN were examined to determine if it was possible to identify resistance to combination therapy," scientists in Ogaki, Japan report.

"One hundred thirty-one patients infected with HCV genotype 1b were enrolled. were given 6 MU of standard IFN alpha-2b at least 2 weeks before initiating combination therapy. Serum HCV RNA levels were measured before, 24 hr after the administration of standard...

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