HIV/AIDS
Findings from The Rockefeller University provide new insights into HIV/AIDS
Published in Hepatitis Weekly, October 25th, 2010
Research findings, 'Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation,' are discussed in a new report. According to recent research published in the journal Nature, "During immune responses, antibodies are selected for their ability to bind to foreign antigens with high affinity, in part by their ability to undergo homotypic bivalent binding. However, this type of binding is not always possible."
"For example, the small number of gp140 glycoprotein spikes displayed on the surface of the human immunodeficiency virus (HIV) disfavours homotypic bivalent antibody binding. Here we show that during the human antibody response to...
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Source: Hepatitis Weekly (2010-10-25)
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