Hepatitis C Virus

New findings from National Research Council describe advances in hepatitis C virus

Published in Hepatitis Weekly, November 8th, 2010

"The hepatitis C virus (HCV) is a global health problem, with limited treatment options and no vaccine available. HCV uses components of the host cell to proliferate, including lipid droplets (LD) onto which HCV core proteins bind and facilitate viral particle assembly," investigators in Ottawa, Canada report.

"We have measured the dynamics of HCV core protein-mediated changes in LDs and rates of LD movement on microtubules using a combination of coherent anti-Stokes Raman scattering (CARS), two-photon fluorescence (TPF), and differential interference contrast (DIC) microscopies. the HCV core protein induces rapid increases in LD size. Particle tracking experiments show...

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Source: Hepatitis Weekly (2010-11-08)

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