Hepatitis
Data on hepatitis detailed by N.S. Eyre and co-authors
Published in Hepatitis Weekly, December 6th, 2010
2010 DEC 6 -- A new study, 'The SR-BI partner PDZK1 facilitates hepatitis C virus entry,' is now available. "Entry of hepatitis C virus (HCV) into hepatocytes is a multi-step process that involves a number of different host cell factors. Following initial engagement with glycosaminoglycans and the low-density lipoprotein receptor, it is thought that HCV entry proceeds via interactions with the tetraspanin CD81, scavenger receptor class B type I (SR-BI), and the tight-junction proteins claudin-1 (CLDN1) and occludin (OCLN), culminating in clathrin-dependent endocytosis of HCV particles and their pH-dependent fusion with endosomal membranes," researchers in Adelaide, Australia...
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Source: Hepatitis Weekly (2010-12-06)
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